In his latest "Ask Me Anything" episode, Matt is once again joined by Dr. Eti Ben Simon to respond to a variety of audience questions, beginning with the role of AI in sleep medicine. Together, they explore how AI is currently being used to improve the accuracy and efficiency of sleep stage scoring, and how it shows promise in diagnosing sleep apnea and personalizing treatment plans. Matt highlights the potential for AI to integrate with smart home technology and predict an individual's risk of developing sleep disorders based on genetics, lifestyle, and environmental data. He also discusses the development of AI-driven therapeutic interventions like digital therapists and brain-computer interfaces to modulate sleep.

Further responses touch upon the impact of sleep deprivation on ethical decision-making and the unique sleep challenges faced by astronauts in space. Matt and Dr. Ben Simon go on to consider the effects of disrupted circadian rhythms, microgravity, and CO2 buildup on astronauts' sleep quality. Finally, they engage in a playful thought experiment, each sharing their desired sleep superpower, ranging from sleep exchange to insightful dreams that provide instant solutions upon waking.

Tired of untrustworthy protein shakes? Show sponsor Puori prioritizes quality: hormone-free, GMO-free, and pesticide-free. Every batch is third-party tested for 200+ contaminants - you can even scan the QR code for lab results! Matt recommends the addictive dark chocolate flavor with 21g of protein. Ready to experience the Puori difference? Matt’s listeners get 20% off, so visit puori.com/mattwalker today!

Another great sponsor of the show is AG1, a comprehensive nutritional drink trusted by thousands worldwide, including Matt! For nearly four years and counting, he has relied on AG1 to fuel his post-workout routine with its powerhouse blend of over 75 essential minerals, vitamins, probiotics, and prebiotics, meticulously crafted to support your daily nutritional needs. AG1 is registered and approved by the Therapeutic Goods Administration, boasting GMP badges for quality assurance. As a special offer for our listeners, when you try AG1, you'll receive a complimentary one-year supply of both Vitamin D and K2, and with your first subscription, you'll also receive five free AG1 travel packs! Visit AG1 to explore AG1's range of offerings and claim your exclusive offer.

Matt is only too happy to share the fact that launching his sleep-related merchandise sales was incredibly smooth, thanks to show sponsor Shopify and their integrated sales and inventory system. And now, just for you, Shopify is generously offering an exclusive trial at shopify.com/mattwalker. Whether it's online or in-person sales, Shopify simplifies it all. So, be sure to stop in at shopify.com/mattwalker to start your exclusive journey now!

As always, if you have thoughts or feedback you’d like to share, please reach out to Matt on Instagram.

Matt: Instagram @drmattwalker or on X @sleepdiplomat

Eti: X @etoosh, Instagram https://www.instagram.com/eti_bensimon/, or email at etoosh@gmail.com

Welcome back to a new episode of the Matt Walker Podcast, where we revisit the often-discussed topic of catch-up sleep. We delve into the complexities of weekend catch-up sleep, exploring a recent study of 91,000 participants that suggests a potential link between compensatory weekend sleep and a reduced risk of heart disease. While this news offers a glimmer of hope, it's crucial to understand this benefit within the context of existing research. Studies like that of Dr. Ken Wright at the University of Colorado Boulder show weekend catch-up sleep only recovers a small percentage of sleep debt and doesn’t fully reverse the damage of weekday sleep deprivation on other critical bodily systems. We explore the impact of short sleep and weekend catch-up sleep on circadian rhythms, food consumption, blood sugar regulation, and deep sleep. This nuanced perspective emphasizes the importance of prioritizing consistent, sufficient sleep throughout the entire week for optimal health.

Please note that Matt is not a medical doctor, and none of the content in this podcast should be considered medical advice in any way, shape, or form, nor prescriptive in any way.

One of our sponsors this week is the biochemical electrolyte drink company LMNT, and they are very kindly offering eight free sample packs when you purchase any one of their orders at drinklmnt.com/mattwalker. LMNT is an electrolyte sports drink that I can get behind - it's created from the basis of science, and it has no sugar, no coloring, and no artificial ingredients – all qualities that are so important to maintaining your blood biochemical balance. If you want to give LMNT a try, just head on over to drinklmnt.com/mattwalker and get your eight free samples with your first purchase.

I have to tell you, launching my sleep-related merchandise sales was incredibly smooth, thanks to our new sponsor Shopify and their integrated sales and inventory system. And now, just for you, Shopify is generously offering an exclusive trial at shopify.com/mattwalker. Whether it's online or in-person sales, Shopify simplifies it all. So, be sure to stop in at shopify.com/mattwalker to start your exclusive journey now!

As a health fanatic, my kryptonite has always been bread. Then I discovered Hero Bread: zero net carbs, zero sugar, and packed with fiber! For years, I've enjoyed their fluffy loaves (my favorite topped with tomatoes, balsamic, and parmesan). Now, you can try it too! Hero Bread offers a delicious variety of healthy bread options, from tortillas and wraps to bagels and dinner rolls. Ready to enjoy bread again? Get 10% off your order at hero.co using code MATTWALKER.

As always, if you have thoughts or feedback you’d like to share, please reach out to Matt on Instagram.

Matt: Instagram @drmattwalker or on X @sleepdiplomat

Matt Walker welcomes Dr. Ranji Varghese to the podcast this week for an in-depth conversation about sleep and prescription sleeping pills. A psychiatrist specializing in sleep medicine, Dr. Varghese begins by discussing his entry into the field which was sparked by a fascination with sleep and wake circadian rhythms. He goes on to highlight the Minnesota Regional Sleep Disorder Center's focus on parasomnias, particularly REM Sleep Behavior Disorder, emphasizing the intersection of neuroscience, physiology, and psychology in sleep medicine.

As you will hear, sleeping pills, prescribed to initiate or maintain sleep, are typically used as a last resort for insomnia after other treatments fail. Dr. Varghese explains they work by modulating brain activity, often targeting neurotransmitters like GABA or melatonin receptors. He details two main classes: benzodiazepines (like Restoril and Ativan) and non-benzodiazepines (Z-drugs like Ambien and Lunesta), outlining their mechanisms, benefits, and risks. His powerful personal anecdote and the discussion of complex sleep-related behaviors underscore the critical need for careful consideration and informed decision-making when using these medications.

Please note that Matt is not a medical doctor, and none of the content in this podcast should be considered medical advice in any way, shape, or form, nor prescriptive in any way.

Long-time show sponsor LMNT is Matt Walker’s go-to for a sugar-free electrolyte mix. With the perfect electrolyte balance and science-backed formulation, LMNT is a product Matt trusts daily, adding it to his workouts and protein shakes. And now, for a seasonal twist, their Chocolate Medley range is back with flavors like Chocolate Mint and Matt’s favorite, Chocolate Raspberry. Get a free sample pack with any purchase at drinklmnt.com/mattwalker—just use his link to try it yourself!

Another great sponsor of the show is AG1, a comprehensive nutritional drink trusted by thousands worldwide, including Matt! For nearly four years and counting, he has relied on AG1 to fuel his post-workout routine with its powerhouse blend of over 75 essential minerals, vitamins, probiotics, and prebiotics, meticulously crafted to support your daily nutritional needs. AG1 is registered and approved by the Therapeutic Goods Administration, boasting GMP badges for quality assurance. As a special offer for our listeners, when you try AG1, you'll receive a complimentary one-year supply of both Vitamin D and K2, and with your first subscription, you'll also receive five free AG1 travel packs! Visit AG1 to explore AG1's range of offerings and claim your exclusive offer.

As always, if you have thoughts or feedback you’d like to share, please reach out to Matt on Instagram.

Matt: Instagram @drmattwalker or on X @sleepdiplomat

Connect with Dr. Varghese:
Instagram: @docvarghese
X: @docvarghese

Minnesota Regional Sleep Disorders Center:
https://www.hennepinhealthcare.org/specialty/minnesota-regional-sleep-disorders-center/
IIT-MN: https://iit-mn.com/