In this recording introducing the Japanese-language series of videos, JACC Executive Associate Editor Mitsuaki Sawano, MD, speaks with Shun Kohsaka, MD, FACC, and Shingo Matsumoto, MD, on topics from the effect of US government funding cuts on Japanese researchers to an in-depth discussion of the FINE-ARTS trial published in JACC, "Initial Decline in Glomerular Filtration Rate with Finerenone in HFpEF and HFmrEF: A Pre-Specified Analysis of FINEARTS-HF".

In this second entry in the JACC-Baran Japanese language series, JACC Executive Associate Editor Mitsuaki Sawano, MD, Shun Kohsaka, MD, FACC, and Yuichi Shimada, MD, MPH, speak on topics ranging from all things Super Bowl to Dr. Shimada’s recently published JACC paper, Comprehensive Proteomic Profiling of Human Myocardium Reveals Signaling Pathways Dysregulated in Hypertrophic Cardiomyopathy.

Dr. Valentin Fuster discusses the February 2025 issue of JACC, which focuses on advancements in heart failure research. The discussion covers five key sections: heart failure with preserved ejection fraction, hypertrophic cardiomyopathy, cardiac amyloidosis, standardization of kidney function, and ICD therapy for primary prevention in heart failure patients. Experts explore emerging therapies, diagnostic thresholds, and the potential impact of blood pressure and genetics on patient outcomes, underscoring the need for comprehensive approaches in managing these complex conditions.

In this February 18, 2025 issue of the JACC, Dr. Valentin Fuster presents groundbreaking studies on topics such as biodegradable polymer stents, myocardial fibroblast activation after heart attacks, and the role of microaxial flow pumps in treating cardiogenic shock. The issue also explores the dangers of ozone exposure on arterial stiffness and highlights expert consensus on arrhythmia monitoring after strokes, offering valuable insights for both cardiology practitioners and researchers.

In this podcast, Dr. Valentin Fuster discusses the Target for NA trial, which compares biodegradable polymer stents to second-generation drug-eluting stents for coronary intervention. While the results showed the biodegradable stents were non-inferior in preventing target lesion failure, questions remain regarding their real-world performance and procedural handling in clinical practice.

In this podcast, Dr. Valentin Fuster discusses a groundbreaking study by Dr. Anna Barton and her team on myocardial fibroblast activation following acute myocardial infarction. Using advanced imaging techniques, the research uncovers how fibroblast activity plays a critical role in heart remodeling, revealing that fibrosis is dynamic and may offer new therapeutic opportunities for preventing heart failure and improving long-term recovery after heart attacks.

In this podcast, Dr. Valentin Fuster discusses a study on the use of the microaxial flow pump (Impella) in treating older patients with cardiogenic shock following a myocardial infarction. The findings suggest that while the Impella pump can reduce mortality in younger patients, its effectiveness diminishes in those over 77, highlighting the need for age-based patient selection to optimize outcomes in this complex condition.

In this podcast, Dr. Valentin Fuster discusses a study examining the impact of short-term ozone exposure on arterial stiffness and cardiovascular health. The research reveals that ozone may reduce oxygen availability, triggering compensatory responses like increased red blood cell count, which contributes to arterial stiffness, and emphasizes the need for further research into the biological mechanisms linking ozone exposure to cardiovascular diseases.