検索キーワード： 遺伝学

Here is the extraordinary story of the unfolding of life on Earth, told by Michael J. Benton, a world-renowned authority on biodiversity. Ranging over four billion years, Benton weaves together the latest findings on fossils, earth history, evolutionary biology, and many other fields to highlight the great leaps that enabled life to evolve from microbe to human - big breakthroughs that made whole new ways of life possible - including cell division and multicellularity, hard skeletons, the move to land, the origin of forests, the move to the air.

How is it that a baboon and a blob of slime mould instinctively know what to eat for optimal health, balancing their protein, fat and carb intake in perfect proportions? In new, groundbreaking research that is transforming our understanding of nutrition, animals from locusts to lions and yes, humans too, demonstrate the remarkable science behind appetite.

Biology is undergoing a quiet but profound transformation. Several aspects of the standard picture of how life works—the idea of the genome as a blueprint, of genes as instructions for building an organism, of proteins as precisely tailored molecular machines, of cells as entities with fixed identities, and more—have been exposed as incomplete, misleading, or wrong. In How Life Works, Philip Ball explores the new biology, revealing life to be a far richer, more ingenious affair than we had guessed.

In The Genome Odyssey, Dr. Euan Ashley, Stanford professor of medicine and genetics, brings the breakthroughs of precision medicine to vivid life through the real diagnostic journeys of his patients and the tireless efforts of his fellow doctors and scientists as they hunt to prevent, predict, and beat disease.

In From Darwin to Derrida, evolutionary biologist David Haig explains how a physical world of matter in motion gave rise to a living world of purpose and meaning. Natural selection, a process without purpose, gives rise to purposeful beings who find meaning in the world. The key to this, Haig proposes, is the origin of mutable “texts”―genes―that preserve a record of what has worked in the world. These texts become the specifications for the intricate mechanisms of living beings.

Scientists' understanding of life is progressing more rapidly than at any point in human history, from the extraordinary decoding of DNA to the controversial emergence of biotechnology. Featuring pioneering biologists, geneticists, physicists, and science writers, Life explains just how far we've come - and takes a brilliantly educated guess at where we're heading.

Few people know much about stem cell research beyond the ethical questions raised by using embryos. But in the last decade, stem cell research has made huge advances toward eliminating some of our most intractable diseases. Now this sweeping and accessible book introduces us to this cutting-edge science, which will revolutionize medicine and change the way we think about and treat disease.

Experts agree on the value of genetic testing when there is a family history of disease, or if the patient has an illness frequently caused by a mutation. Knowing the disease mutation lets family members find out if they have it too and need preventive care. The book explains that doctors can order tests with genetic counseling at relatively low cost and how this will help them prescribe preventive actions, make earlier diagnoses, and get better outcomes.

One of the biggest discoveries in physics, the quest for the Higgs boson demonstrates the value of a good theory. In July 2012, a Higgs-like particle was found near the energies scientists predicted. Now, armed with better evidence and better questions, the scientific process continues. In this audiobook, we’ve gathered our best reporting to explain that process - the theories, the search, the discovery, and the ongoing questions.

In the early 1800s, a century before there was any concept of the gene, physicians in insane asylums began to record causes of madness in their admission books. Almost from the beginning, they pointed to heredity as the most important of these causes. As doctors and state officials steadily lost faith in the capacity of asylum care to stem the terrible increase of insanity, they began emphasizing the need to curb the reproduction of the insane. They became obsessed with identifying weak or tainted families and anticipating the outcomes of their marriages.

This Very Short Introduction uncovers the history of our understanding of sexual selection, from Darwin's key insights to the modern day. Considering the investment animals place on reproduction, variation in mating systems, sexual conflict, and the origin of sexual dimorphism, authors Marlene Zuk and Leigh Simmons discuss questions such as whether females can really choose between males on aesthetic grounds and how sexual conflict is resolved in different species.

Breakthroughs in genetics present us with a promise and a predicament. The promise is that we will soon be able to treat and prevent a host of debilitating diseases. The predicament is that our newfound genetic knowledge may enable us to manipulate our nature - to enhance our genetic traits and those of our children. Although most people find at least some forms of genetic engineering disquieting, it is not easy to articulate why.

Epigenetics is the science of living DNA, charting the chemical pathways that spur DNA into action by turning genes on and off. While the Human Genome Project of the early 2000s was hailed as the key to understanding human heredity and disease, that historic effort was just the beginning. It has taken epigenetics to fill in the picture, explaining how the fixed code of our genome is implemented in countless living processes.

Control is a book about what geneticist Adam Rutherford calls “a defining idea of the twentieth century.” Inspired by Darwin’s ideas about evolution, eugenics arose in Victorian England as a theory for improving the British population, and quickly spread to America. With disarming wit and scientific precision, Rutherford explains why eugenics still figures prominently in the twenty-first century, despite its genocidal past. And he confronts insidious recurring questions, revealing the intellectual bankruptcy of the idea, and the scientific impossibility of its realization.

Over 500,000 years ago, a single gene mutated. It spread over time, becoming critical in the journey transforming our earliest ancestors into fully modern humans, capable of navigating the entire planet and beyond. Then just a few thousand years ago, humans gradually outsourced knowledge to writing, and we displaced art and music from the heart of learning. This is the extraordinary story of the discovery of a supergene that makes us uniquely human.

"Guerras CRISPR: Cómo la Edición Genética Revolucionará la Guerra" es una obra de no ficción que explora el asombroso y aterrador potencial de la tecnología CRISPR en el campo de batalla. A través de un análisis detallado, el libro examina cómo la manipulación genética puede dar lugar a soldados mejorados, capaces de hazañas físicas y cognitivas que antes eran imposibles. Además de los avances científicos, se abordan los dilemas éticos, el impacto estratégico en los conflictos militares y las consecuencias globales.

In The Genetic Lottery, Harden introduces listeners to the latest genetic science, dismantling dangerous ideas about racial superiority and challenging us to grapple with what equality really means in a world where people are born different. Weaving together personal stories with scientific evidence, Harden shows why our refusal to recognize the power of DNA perpetuates the myth of meritocracy, and argues that we must acknowledge the role of genetic luck if we are ever to create a fair society.

Penguin presents the audiobook edition of Blueprint, written and read by Robert Plomin. The blueprint for our individuality lies in the 1 percent of DNA that differs between people. Our intellectual capacity, our introversion or extraversion, our vulnerability to mental illness, even whether we are a morning person - all of these aspects of our personality are profoundly shaped by our inherited DNA differences.

In this groundbreaking approach to the evolution of all life, Richard Dawkins shows how the body, behaviour, and genes of every living creature can be read as a book – an archive of the worlds of its ancestors. A perfectly camouflaged desert lizard has a desiccated landscape of sand and stones ‘painted’ on its back. Its skin can be read as a description of ancient deserts in which its ancestors survived – and, before that, of the worlds of its more remote ancestors: a genetic book of the dead.

The body is magnificent but it doesn't come with a lifetime warranty or an operating manual. You're the result of millions of years of evolution, but many of the adaptations that helped your ancestors survive are now working overtime to accelerate the aging process. The assumption here is that we are our genes and therefore trapped by the past. The good news is that your genetic code - the DNA sequence that is the biochemical basis of heredity - can play a minor role in the way you age.