Intermittent fasting has become one of the most popular weight loss strategies but does it work better than traditional calorie restriction? This burning question finally has an answer, thanks to a groundbreaking year-long clinical trial.

Join Holly and Jim as they interview Victoria Catenacci, the lead researcher behind this landmark study on 4:3 intermittent fasting. As a physician and clinical researcher at the University of Colorado Anschutz Medical Campus, Dr. Catenacci has spent years investigating whether eating very little three days a week (while eating normally the other four days) produces better results than daily calorie restriction. After seven years of research, the results are finally in – and they might surprise you.

• What 4:3 intermittent fasting means (and how it differs from other fasting methods)
• The surprising finding about which approach produced more weight loss after one year
• Why women seemed to benefit more from intermittent fasting than men
• Whether fasting three days a week leads to muscle loss compared to daily restriction
• The truth about whether intermittent fasting triggers binge eating behaviors
• The unexpected finding about which approach might be easier to stick with in the long-term
• How to safely exercise on fasting days versus non-fasting days
• The simple strategy that made fasting days more manageable for study participants

This conversation cuts through the hype to reveal what science says about intermittent fasting for sustainable weight loss. Whether you're curious about trying fasting or want evidence-based weight management strategies, this episode delivers valuable insights from the researcher who led this revolutionary study.

Are you moving enough? While many of us focus on weight loss goals, we're often missing a critical piece of the puzzle: our drastic decline in daily movement. In this episode, Holly and Jim reveal how physical activity has quietly disappeared from our lives over the past decades.

Did you know that in the 1960s, people burned 300-400 more calories daily without ever setting foot in a gym? Join Holly and Jim as they explore America's "physical activity report card" and share startling statistics about how technology and modern lifestyles have engineered movement out of our daily routines. You'll discover practical strategies to reclaim physical activity in a world designed for sitting.

• How work and transportation-related movement has drastically declined since the 1960s
• Why meeting the recommended 150-300 minutes of weekly activity is harder than you think
• The three critical buckets of physical activity you need to consider
• Why strength training is the most overlooked form of exercise (with a surprising home "gym" equipment everyone owns)
• Personal challenges Jim and Holly face with staying active
• Why high-energy living (more calories in AND out) is easier to maintain than low-energy living

Are you frustrated by conflicting weight loss advice? Tired of hearing about miracle diets and quick fixes that never seem to work? Get ready for a conversation that cuts through the noise and gets to the heart of weight management.

In this episode, we're diving deep into the science of energy balance with Dr. Keith Frayn, Emeritus Professor of Human Metabolism at the University of Oxford. Dr. Frayn brings decades of research experience and a refreshingly clear perspective to one of the most confusing topics in nutrition: How do we really lose weight and keep it off?

With his latest book "A Calorie is a Calorie," Dr. Frayn challenges popular myths and provides a scientifically grounded approach to understanding weight management that goes beyond simple diet trends. Prepare to have your assumptions challenged and gain insights that could transform your approach to health and nutrition.

• Why "calories in, calories out" isn't as simple as it sounds
• Why our bodies are still evolutionarily wired to defend against starvation
• Metabolism and weight gain myths
• How modern environment influences our ability to maintain a healthy weight
• The role of physical activity beyond just burning calories
• Insights into new weight loss medications and their potential limitations
• Why precision nutrition might not be the magic solution we're hoping for

• Book: "A Calorie is a Calorie: The Inescapable Science that Controls Our Body Weight" by Dr. Keith Frayn