In this episode, we explore stDyer, a deep learning framework for spatially resolved transcriptomics that blends Gaussian Mixture VAEs with dynamic graph embeddings. Developed with scalability in mind, stDyer reveals hidden spatial domains in tissue by adapting to boundaries and leveraging GPU acceleration. This AI-generated summary was crafted through prompt engineering and reviewed by a contributing author to ensure accuracy. Views expressed reflect individual interpretation and not official peer-reviewed findings or institutional positions.
URL: https://genomebiology.biomedcentral.com/articles/10.1186/s13059-025-03503-y