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This is part one of a two-part mini-series on fertility and reproductive health, with next week's guest, Dr. Paula Amato, focusing on the female side of the equation. Paul Turek is a world-renowned expert in male fertility and reproductive health, the founder and medical director of the Turek Clinic, and host of the Talk with Turek podcast. In this episode, Paul explores the topic of male fertility, offering a detailed look at the complex and highly coordinated process of conception and the many challenges sperm face on their journey to fertilizing an egg. He shares fascinating insights into how sperm work together to navigate the female reproductive tract, how environmental factors like heat, stress, and toxins impact sperm quality, and what men can do to improve their reproductive health. Paul also dispels common myths about testosterone replacement therapy and its effects on fertility, providing strategies for preserving fertility while on TRT. The episode also highlights cutting-edge advances in reproductive medicine, from genetic testing and sperm sorting to emerging treatments for infertility.

We discuss:

• The incredibly complex and hostile journey sperm must take to fertilize an egg [3:00];
• How sperm are made: meiosis, genetic variation, and the continuous renewal influenced by environmental factors [9:00];
• The built-in filter that weeds out genetically abnormal sperm [14:45];
• How sperm are finalized in form and function: tail formation, energy storage, and chemical sensing abilities [18:30];
• How to optimize conception through the timing of sex, ejaculation frequency, and understanding the sperm lifecycle [26:30];
• Male infertility and Paul’s diagnostic approach: detailed history, a physical exam, and identifying red flags [33:30];
• Viral infections that can affect the testes and potentially lead to sterility [40:30];
• Semen analysis: morphology, motility, and hormonal clues to male fertility [45:45];
• Effects of medication, microplastics, stress, and exercise on fertility [57:15];
• Testosterone replacement therapy (TRT) and male fertility [1:06:00];
• Restoring fertility after prolonged use of exogenous testosterone [1:25:00];
• Effects of heat and cold exposure on fertility and sperm quality [1:36:00];
• How different levels of exercise—especially cycling—affect male fertility [1:41:45];
• How alcohol, marijuana, and nicotine affect male fertility [1:46:00];
• Why type 2 diabetes is a risk factor for male infertility [1:50:00];
• How varicoceles—a common cause of male infertility—are diagnosed and treated [1:51:15];
• Genetic factors that affect fertility [1:54:00];
• The impact of lifestyle and environmental exposures on fertility [1:56:30];
• The evidence (or lack thereof) behind stem cell and PRP therapies for male infertility, and how lifestyle and non-invasive interventions often lead to successful conception [2:00:30];
• Considerations for sperm banking, and how paternal age impacts fertility planning and offspring health [2:05:00];
• Semen quality as a biomarker: linking male fertility, longevity, and preventative health through Medicine 3.0 and epigenetics [2:14:45]; and
• More.

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View the Show Notes Page for This Episode

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Kyler Brown is a sports rehab chiropractor who specializes in injury recovery, pre- and post-surgical rehabilitation, and guiding clients from rehab back to peak performance. As co-founder of the private training program 10 Squared alongside Peter, Kyler shares his approach to injury prevention and performance optimization—highlighting how overlooked movement patterns can quietly lead to chronic issues over time. He outlines a practical framework for assessing and treating individuals, highlights the importance of understanding movement dynamics and asymmetries, and discusses personalized rehab strategies through real-world case studies. The conversation also explores the psychological side of recovery, including the role of fear and mental barriers in rehabilitation. Kyler shares actionable tools to evaluate movement patterns and implement training strategies that support long-term strength and health.

A companion video series demonstrating exercises for common problem areas—such as the lower back, neck, shoulders, and knees—is available exclusively to subscribers on the show notes page.

We discuss:

• The personalized rehab strategy for Peter’s shoulder surgery that sparked creation of a training program called 10 Squared [3:00];
• Training for the marginal decade: why precision and purpose are essential for quality of life [11:00];
• The Centenarian Decathlon: how training for long-term capacity enhances both current and future quality of life [18:00];
• How the shortcomings of conventional rehab and performance systems led to the creation of 10 Squared, a personalized training model focused on long-term physical capacity and individualized care [23:45];
• Case study: how personalized assessment and treatment at 10 Squared helps uncover the root causes of injuries [31:00];
• The role of the “core” in movement and injury prevention, and the importance of training stability before strength [40:15];
• The layered assessment process used at 10 Squared to determine whether a person is ready to perform dynamic movements [47:45];
• Case study: the rehab plan designed to treat a hamstring injury while preserving fitness and preventing reinjury [51:45];
• Training approach for clients with minimal training history: risk reduction, habit-building, and long-term consistency [55:30];
• How to train foot reactivity, tendon resilience, and explosive capacity in a safe, progressive way [1:00:00];
• Peter’s foot and ankle pain: how to diagnose, treat, and strengthen the lower extremities [1:04:15];
• How fear and perception influence recovery, what drives back pain, and when to choose surgery vs. treatment [1:13:15];
• Could AI and app technology eventually deliver an individualized rehab and training experience? [1:22:30];
• Kyler’s professional evolution from traditional chiropractic care to a degree-agnostic, performance-based rehab philosophy [1:25:00];
• How 10 Squared provides precision rehab and training in a remote format [1:30:30];
• How Peter resolved a severe back pain flare-up using DNS-guided isometric exercise instead of passive treatments [1:33:15];
• How to identify and treat common joint pain (neck, back, knee, shoulder) using a rehab framework that strengthens supporting structures and helps avoid surgery [1:39:00]; and
• More.

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