Drs Catherine Liu and Joshua Hill of the Fred Hutchinson Cancer Center discuss their new Series of papers on the prevention and management of infections in people who are immunocompromised, with a focus on prevention of infections and diagnostic and antimicrobial stewardship.

Read the Series papers:

https://www.thelancet.com/journals/laninf/article/PIIS1473-3099(25)00345-7/fulltext?dgcid=buzzsprout_icw_podcast_August_25_laninf

https://www.thelancet.com/journals/laninf/article/PIIS1473-3099(25)00311-1/fulltext?dgcid=buzzsprout_icw_podcast_August_25_laninf

Read the linked Comment:

https://www.thelancet.com/journals/laninf/article/PIIS1473-3099(25)00355-X/fulltext?dgcid=buzzsprout_icw_podcast_August_25_laninf

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Lilian Tina Minja and Norbert Heinrich discuss the SUDUCO and DECODE trials in The Lancet Infectious Diseases on two new promising TB drugs, sutezolid and delpazolid, respectively. They also discuss the wider implications of the findings of these trials for TB drug development and treatment.

Read the trials:

https://www.thelancet.com/journals/laninf/article/PIIS1473-3099(25)00213-0/fulltext?dgcid=buzzsprout_icw_podcast_July_25_laninf

https://www.thelancet.com/journals/laninf/article/PIIS1473-3099(25)00289-0/fulltext?dgcid=buzzsprout_icw_podcast_July_25_laninf

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Leonardo Basso and Juan Pablo Torres discuss their study in The Lancet Infectious Diseases on the effectiveness and impact of the first season of Chile's national immunisation programme with nirsevimab. They discuss the evidence that led to the design and implementation of the programme, its impact on RSV burden and the Chilean health system, and lessons for other countries in the region and beyond.

Read the full article at: https://www.thelancet.com/journals/laninf/article/PIIS1473-3099(25)00233-6/fulltext?dgcid=buzzsprout_icw_podcast_10-06-25_laninf

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