
Decibel Bio: Disrupting a $100 billion industry
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Some highlights
- Biggest driver for startup success: identify the unique business approach, the value proposition, including how to reach consumers, and then fit the science around that.
- Sound Agriculture: Core focus is using small molecule chemistry and natural products to signal to microbes for a more efficient and productive crop.
- How Decibel Bio is different: This is a nucleic acid, biotech platform, aiming to disrupt the $100 billion seed industry using plant epigenetics to control the crop genome, turning genes on and off, during the growing season.
- Targeted crop traits: For example, drought tolerance, by turning on aquaporins, the proteins needed to transport water across cell membranes and cell tissues.
- End product: Traits would be delivered via a crop spray, instead of a seed. The spray could be marketed alongside the seed, as a package, or as an alternative vehicle for trait investment.
- Success evidence: Decibel is gearing up for field trials in North America, at dozens of different sites, to develop a product pipeline. The main focus is corn and soy.
- Tariffs: “Trade protectionism is not good for ag. In U.S. agriculture, especially in corn and soy, we rely on export markets. If you want to spook a room of farmers, you walk in and start talking about tariffs.”
- Microbials impacts on yields: Gains from microbials are real but small – say 2 bushels of corn per acre. “The benefit is marginal. It’s a nice to have. In a tough farm economy, the nice to haves are the first to go.”
- Next 10 years of crop production: We’ll see an automation of the whole agronomic process. Today – you walk a field, spot disease, and recommend a spray. In future – big soil, weather, crop, imagery data will be collected from the field, processed by predictive AI-based models into interventions in an automated loop.
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