They were madly in love. The perfect couple. That was the story everyone in South River believed...until Gin Talcott and Adam Archer are found shot in their bed. Adam is dead at the scene. Gin is fighting for her life. Detectives Greta Jessup and Finn Pate are assigned to the case. Greta has a long history with Gin’s first husband, Eddie, and is determined to protect his 18-year-old twins. Piper discovered the bodies. Daniel is missing—and so is Adam’s gun.

After the killing of a prominent mob lawyer, NYPD homicide detectives Jacob Jackson and Caitlin Grimes start receive chilling, written “rules” for how to commit the perfect murder. "Rule number one for the perfect murder: Evidence is your enemy. Leave none behind." Jackson (Reid Scott) and Grimes (Cobie Smulders) race to find the killer, setting them on a collision course with the city’s crime underbelly, and a perpetrator who seems happy to toy with them. “Rule number two. No crimes of passion. The perfect murder is always business, never pleasure.”

Sydney Shaw, like every single woman in New York, has terrible luck with dating. She's seen it all: men who lie in their dating profile, men who stick her with the dinner bill, and worst of all, men who can't shut up about their mothers. But finally, she hits the jackpot. Her new boyfriend is utterly perfect. He's charming, handsome, and works as a doctor at a local hospital. Sydney is swept off her feet.

When the Dickenson clan sits down for Thanksgiving dinner in 2016, it is the last holiday where their tight-knit family will ever be the same. Oldest brother Pete and his wife are expecting their first child. Youngest sibling Sophie is too busy running her restaurant. The Little Plum, to bother with any kind of social life. And middle child Charlie’s happy, uncomplicated life as a midwestern science professor is upended when his wife Annette is diagnosed with a terminal illness. Knowing this will be her last Thanksgiving, Annette asks Sophie to look after Charlie after she’s gone.

Newlyweds Tricia and Ethan are searching for the house of their dreams. But when they visit the remote manor that once belonged to Dr. Adrienne Hale, a renowned psychiatrist who vanished without a trace four years earlier, a violent winter storm traps them at the estate… with no chance of escape until the blizzard comes to an end. In search of a book to keep her entertained until the snow abates, Tricia happens upon a secret room. One that contains audio transcripts from every single patient Dr. Hale has ever interviewed.